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Of course, older adults, people over age 50 in particular, tend to have the lowest B12 levels, though vegetarians and those who have undergone gastric bypass surgery are also at a higher risk
Crucially, the Pennington study found that Tirzepatide did not significantly impact the metabolic adaptation (slowing down of metabolism) usually observed with weight loss in humans
Many patients find sublingual (under-the-tongue) B12 effective because it bypasses stomach absorption entirely
Takahisa Hirose has received research grants from Sumitomo Pharma Co., Ltd
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